iPTMnet Report for Q9Y6A2 (CYP46A1)
Protein Information
| UniProt AC / UniProt ID | Q9Y6A2 / CP46A_HUMAN |
| Protein Name | Cholesterol 24-hydroxylase |
| Gene Name | Name: CYP46A1 Synonyms:CYP46; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y6A2 |
| PRO Name | cholesterol 24-hydroxylase (human) |
| Definition | A cytochrome P450 46A1 that is encoded in the genome of human. |
| Short Label | hCYP46A1 |
| Category | organism-gene |
DAG ViewQ9Y6A2 (CYP46A1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T83 | O-Glycosylation | score1 | GlyGen | 30620550 | ||
| T88 | O-Glycosylation | score1 | GlyGen | 30620550 | ||
| S146 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S148 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y341 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y352 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S354 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S148 | N148 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y341 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| S354 | F354 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
