iPTMnet Report for Q9Y692 (GMEB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y692 / GMEB1_HUMAN
Protein Name Glucocorticoid modulatory element-binding protein 1
Gene Name Name: GMEB1
Organism Homo sapiens (Human)

PRO ID PR:Q9Y692
DAG View
PRO Name glucocorticoid modulatory element-binding protein 1 (human)
Definition A glucocorticoid modulatory element-binding protein 1 that is encoded in the genome of human.
Short Label hGMEB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y692 (GMEB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
K110 Ubiquitination PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
S129 Phosphorylation phospho.ELM   PhosphoSitePlus 16964243
K131 Ubiquitination PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
T241 O-Glycosylation GlyGen 35138101, 34019948, 30379171, ...32574038, 30059200, 28657654, 35254053, 35132862, 31492838, 29485866, 35289036, 29351928, 31373491
S249 O-Glycosylation GlyGen 35138101, 34019948, 30379171, ...32574038, 30059200, 28657654, 35254053, 35132862, 31492838, 29485866, 35289036, 29351928, 31373491
R285 Methylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
T373 Phosphorylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
T438 O-Glycosylation GlyGen 35138101, 34019948, 30379171, ...32574038, 30059200, 28657654, 35254053, 35132862, 31492838, 29485866, 35289036, 29351928, 31373491
S441 O-Glycosylation GlyGen 35138101, 34019948, 30379171, ...32574038, 30059200, 28657654, 35254053, 35132862, 31492838, 29485866, 35289036, 29351928, 31373491
T450 O-Glycosylation GlyGen 35138101, 34019948, 30379171, ...32574038, 30059200, 28657654, 35254053, 35132862, 31492838, 29485866, 35289036, 29351928, 31373491
S453 O-Glycosylation GlyGen 34846842, 35138101, 30379171, ...32574038, 34019948, 28657654, 35254053, 35132862, 31492838, 29485866, 35289036, 29351928, 31373491, 30059200
S454 O-Glycosylation GlyGen 35138101, 34019948, 30379171, ...32574038, 30059200, 28657654, 35254053, 35132862, 31492838, 29485866, 35289036, 29351928, 31373491
S457 O-Glycosylation GlyGen 35138101, 34019948, 30379171, ...32574038, 30059200, 28657654, 35254053, 35132862, 31492838, 29485866, 35289036, 29351928, 31373491
S458 O-Glycosylation GlyGen 35138101, 34019948, 30379171, ...32574038, 30059200, 28657654, 35254053, 35132862, 31492838, 29485866, 35289036, 29351928, 31373491
S459 O-Glycosylation GlyGen 35138101, 34019948, 30379171, ...32574038, 30059200, 28657654, 35254053, 35132862, 31492838, 29485866, 35289036, 29351928, 31373491
T464 O-Glycosylation GlyGen 35138101, 34019948, 30379171, ...32574038, 30059200, 28657654, 35254053, 35132862, 31492838, 29485866, 35289036, 29351928, 31373491
S468 O-Glycosylation GlyGen 35138101, 34019948, 30379171, ...32574038, 30059200, 28657654, 35254053, 35132862, 31492838, 29485866, 35289036, 29351928, 31373491
S470 O-Glycosylation GlyGen 35138101, 34019948, 30379171, ...32574038, 30059200, 28657654, 35254053, 35132862, 31492838, 29485866, 35289036, 29351928, 31373491
K538 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T241 M241 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R285 K285 Biomuta DOID:4159 / skin cancer [ cosmic ]
T438 I438 Biomuta DOID:363 / uterine cancer [ icgc ]
S441 F441 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S470 T470 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]