Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y679 / AUP1_HUMAN
Protein Name Lipid droplet-regulating VLDL assembly factor AUP1
Gene Name Name: AUP1
Organism Homo sapiens (Human)

PRO ID PR:Q9Y679
DAG View
PRO Name lipid droplet-regulating VLDL assembly factor AUP1 (human)
Definition A lipid droplet-regulating VLDL assembly factor AUP1 that is encoded in the genome of human.
Short Label hAUP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y679 (AUP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378, 22223895
S5 Phosphorylation PhosphoSitePlus   UniProt 23186163
C22 Methylation IEDB 31844290
T68 Phosphorylation PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
T154 Phosphorylation PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
T260 Phosphorylation PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus   UniProt 18691976, 18669648, 23186163, ...20068231
S292 Phosphorylation PhosphoSitePlus   UniProt 18669648
K322 Ubiquitination PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
S358 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K359 Ubiquitination PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus   UniProt 18669648
T367 Phosphorylation PhosphoSitePlus   UniProt 18691976, 18669648, 23186163
T371 Phosphorylation PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
Y394 Phosphorylation PhosphoSitePlus
Y396 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T260 Phosphorylation HPRD 18691976
S288 Phosphorylation HPRD 18691976, 18669648, 20068231
S292 Phosphorylation HPRD 18669648
T299 Phosphorylation HPRD 18669648
S356 Phosphorylation HPRD 18669648
S362 Phosphorylation HPRD 18669648, 20068231
S363 Phosphorylation HPRD 18669648, 20068231
T367 Phosphorylation HPRD 19413330, 18691976, 18669648, ...20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T68 A68 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K143 N143 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S280 L280 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T299 I299 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K347 N347 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S358 T358 Biomuta DOID:3571 / liver cancer [ cosmic ]
K359 N359 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S363 A363 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K377 E377 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K390 T390 Biomuta DOID:4362 / cervical cancer [ cosmic ]