iPTMnet Report for Q9Y666 (SLC12A7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y666 / S12A7_HUMAN
Protein Name Solute carrier family 12 member 7
Gene Name Name: SLC12A7
Synonyms:KCC4;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y666
DAG View
PRO Name solute carrier family 12 member 7 (human)
Definition A solute carrier family 12 member 7 that is encoded in the genome of human.
Short Label hSLC12A7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y666 (SLC12A7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T25 Phosphorylation PhosphoSitePlus
T30 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S40 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S50 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S62 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S78 Phosphorylation PhosphoSitePlus
Y92 Phosphorylation PhosphoSitePlus
T93 Phosphorylation PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
N312 N-Glycosylation GlyGen 29741879, 24190977
K393 Ubiquitination PhosphoSitePlus
S669 Phosphorylation PhosphoSitePlus
T715 Phosphorylation PhosphoSitePlus
S716 Phosphorylation PhosphoSitePlus
Y735 Phosphorylation PhosphoSitePlus
K757 Ubiquitination PhosphoSitePlus
K809 Ubiquitination PhosphoSitePlus
K893 Ubiquitination PhosphoSitePlus
T926 Phosphorylation PhosphoSitePlus
K937 Ubiquitination PhosphoSitePlus
K943 Ubiquitination PhosphoSitePlus
T968 Phosphorylation PhosphoSitePlus
T973 Phosphorylation PhosphoSitePlus 24393035
T973 Phosphorylation Q9UEW8 (STK39) PhosphoSitePlus 24393035
K976 Ubiquitination PhosphoSitePlus
T980 Phosphorylation PhosphoSitePlus 24393035
T980 Phosphorylation Q9UEW8 (STK39) PhosphoSitePlus 24393035
K985 Ubiquitination PhosphoSitePlus
K990 Ubiquitination PhosphoSitePlus
Y991 Phosphorylation PhosphoSitePlus
T996 Phosphorylation PhosphoSitePlus
S997 Phosphorylation PhosphoSitePlus
K1002 Ubiquitination PhosphoSitePlus
S1006 Phosphorylation PhosphoSitePlus
K1008 Ubiquitination PhosphoSitePlus
S1012 Phosphorylation PhosphoSitePlus
K1030 Ubiquitination PhosphoSitePlus
K1046 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T30 Phosphorylation HPRD 18669648
S40 Phosphorylation HPRD 18669648
S50 Phosphorylation HPRD 18669648
S62 Phosphorylation HPRD 18669648
S960 Phosphorylation HPRD 20068231
T962 Phosphorylation HPRD 20068231
T968 Phosphorylation HPRD 20068231
T980 Phosphorylation HPRD 18767875, 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S62 R62 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
T715 M715 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S716 L716 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T962 I962 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y991 F991 Biomuta DOID:1324 / lung cancer [ cosmic ]