iPTMnet Report for Q9Y639 (NPTN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y639 / NPTN_HUMAN
Protein Name Neuroplastin precursor
Gene Name Name: NPTN
Synonyms:SDFR1,SDR1;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y639
DAG View
PRO Name neuroplastin (human)
Definition A neuroplastin that is encoded in the genome of human.
Short Label hNPTN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y639 (NPTN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N171 N-Glycosylation GlyGen 24190977
N197 N-Glycosylation GlyGen 29741879, 24190977
S199 O-Glycosylation GlyGen 33214551, 34725712, 35289036
N200 N-Glycosylation GlyGen 24190977
Y216 Phosphorylation PhosphoSitePlus
Y220 Phosphorylation PhosphoSitePlus
N229 N-Glycosylation GlyGen   UniProt 29741879, 19349973, 24190977
K235 Ubiquitination PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
N284 N-Glycosylation GlyGen   UniProt 19159218, 24190977
S286 Phosphorylation PhosphoSitePlus
N296 N-Glycosylation GlyGen   UniProt 19159218
K364 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N197 H197 Biomuta DOID:3571 / liver cancer [ cosmic ]
S199 R199 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K244 T244 Biomuta DOID:363 / uterine cancer [ icgc ]
K260 T260 Biomuta DOID:10534 / stomach cancer [ cosmic ]