Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y624 / JAM1_HUMAN
Protein Name Junctional adhesion molecule A precursor
Gene Name Name: F11R
Synonyms:JAM1,JCAM;ORFNames:UNQ264/PRO301;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y624
DAG View
PRO Name junctional adhesion molecule A (human)
Definition A junctional adhesion molecule A that is encoded in the genome of human.
Short Label hF11R
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y624 (F11R) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R86 Methylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus
T100 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
T175 O-Glycosylation PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
N185 N-Glycosylation GlyGen   UniProt 29741879, 19159218
S262 Phosphorylation RLIMS-P 22371556
T273 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S275 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K277 Ubiquitination PhosphoSitePlus
Y280 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 18083107, 30625033, 18669648
S281 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S284 Phosphorylation P17252 (PRKCA) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 21406692, 23186163, 18669648, ...24275569, 26985018, 11027562, 18088087, 20068231
S287 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K292 Ubiquitination PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S34 Phosphorylation P68400 (CSNK2A1) HPRD 7646439
T70 Phosphorylation P17252 (PRKCA) HPRD 7646439
T92 Phosphorylation P17252 (PRKCA) HPRD 7646439
T95 Phosphorylation HPRD 20068231
S133 Phosphorylation HPRD 20068231
T136 Phosphorylation HPRD 20068231
S141 Phosphorylation HPRD 20068231
S142 Phosphorylation HPRD 20068231
T144 Phosphorylation HPRD 20068231
T273 Phosphorylation HPRD 18669648
S275 Phosphorylation HPRD 18669648
Y280 Phosphorylation HPRD 18083107, 19901323, 18669648, ...18707149
S281 Phosphorylation HPRD 18669648
S284 Phosphorylation HPRD 19413330, 18088087, 18767875, ...19664994, 19651622, 18669648, 20166139, 20068231
S287 Phosphorylation HPRD 19413330, 19651622, 18669648, ...20166139, 20068231
S296 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T95 N95 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S98 F98 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T175 M175 Biomuta DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]
N185 S185 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K277 N277 Biomuta DOID:1115 / sarcoma [ tcga ]
S295 L295 Biomuta DOID:2531 / hematologic cancer [ icgc ]