iPTMnet Report for Q9Y624 (F11R)
Protein Information
| UniProt AC / UniProt ID | Q9Y624 / JAM1_HUMAN |
| Protein Name | Junctional adhesion molecule A precursor |
| Gene Name | Name: F11R Synonyms:JAM1,JCAM;ORFNames:UNQ264/PRO301; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y624 |
| PRO Name | junctional adhesion molecule A (human) |
| Definition | A junctional adhesion molecule A that is encoded in the genome of human. |
| Short Label | hF11R |
| Category | organism-gene |
DAG ViewQ9Y624 (F11R) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T30 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| R86 | Methylation | score1 | PhosphoSitePlus | |||
| K97 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T100 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S133 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T175 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N185 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19159218 | ||
| S262 | Phosphorylation | score0 | RLIMS-P | 22371556 | ||
| T273 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S275 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| K277 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y280 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P | 30625033, 18669648, 18083107 | ||
| S281 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
| S284 | Phosphorylation | P17252 (PRKCA) | score4 | phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 21406692, 18088087, 18669648, ... | |
| S287 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| K292 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S295 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S296 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S34 | Phosphorylation | P68400 (CSNK2A1) | score1 | HPRD | 7646439 | |
| T70 | Phosphorylation | P17252 (PRKCA) | score1 | HPRD | 7646439 | |
| T92 | Phosphorylation | P17252 (PRKCA) | score1 | HPRD | 7646439 | |
| T95 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S133 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T136 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S141 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S142 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T144 | Phosphorylation | score0 | HPRD | 20068231 | ||
| N185 | N-Glycosylation | score1 | PRO | 29741879 | ||
| T273 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S275 | Phosphorylation | score0 | HPRD | 18669648 | ||
| Y280 | Phosphorylation | score0 | HPRD | 18083107, 19901323, 18669648, ... | ||
| S281 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S284 | Phosphorylation | score0 | HPRD | 19413330, 18088087, 18767875, ... | ||
| S287 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 18669648, ... | ||
| S296 | Phosphorylation | score0 | HPRD | 19413330 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R86 | Q86 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| R86 | W86 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T95 | N95 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S98 | F98 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T175 | M175 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
| N185 | S185 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| T273 | A273 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K277 | N277 | Biomuta | [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1115 / sarcoma [ icgc ] | |
| S295 | L295 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] |
