iPTMnet Report for Q9Y623 (MYH4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y623 / MYH4_HUMAN
Protein Name Myosin-4
Gene Name Name: MYH4
Organism Homo sapiens (Human)

PRO ID PR:Q9Y623
DAG View
PRO Name myosin-4 (human)
Definition A myosin-4 that is encoded in the genome of human.
Short Label hMYH4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y623 (MYH4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T64 Phosphorylation PhosphoSitePlus
T69 Phosphorylation PhosphoSitePlus
Y163 Phosphorylation PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
Y195 Phosphorylation PhosphoSitePlus
T198 Phosphorylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
T258 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
Y269 Phosphorylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
T356 Phosphorylation PhosphoSitePlus
Y362 Phosphorylation PhosphoSitePlus
T381 Phosphorylation PhosphoSitePlus
Y389 Phosphorylation PhosphoSitePlus
Y424 Phosphorylation PhosphoSitePlus
K505 Acetylation PhosphoSitePlus
Y556 Phosphorylation PhosphoSitePlus
T607 Phosphorylation PhosphoSitePlus
Y612 Phosphorylation PhosphoSitePlus
T664 Phosphorylation PhosphoSitePlus
Y719 Phosphorylation PhosphoSitePlus
S732 Phosphorylation PhosphoSitePlus
S742 Phosphorylation PhosphoSitePlus
K744 Acetylation PhosphoSitePlus
S746 Phosphorylation PhosphoSitePlus
T790 Phosphorylation PhosphoSitePlus
Y820 Phosphorylation PhosphoSitePlus
K857 Methylation PhosphoSitePlus
K862 Methylation PhosphoSitePlus
K922 Acetylation PhosphoSitePlus
S952 Phosphorylation PhosphoSitePlus
K955 Acetylation PhosphoSitePlus
K956 Acetylation PhosphoSitePlus
T964 Phosphorylation PhosphoSitePlus
T983 Phosphorylation PhosphoSitePlus
T992 Phosphorylation PhosphoSitePlus
T997 Phosphorylation PhosphoSitePlus
K1030 Methylation PhosphoSitePlus
S1041 Phosphorylation PhosphoSitePlus
K1046 Acetylation PhosphoSitePlus
K1087 Methylation PhosphoSitePlus
K1097 Methylation PhosphoSitePlus
K1111 Acetylation PhosphoSitePlus
K1113 Acetylation PhosphoSitePlus
R1130 Methylation PhosphoSitePlus
S1132 Phosphorylation PhosphoSitePlus
S1141 Phosphorylation PhosphoSitePlus
S1144 Phosphorylation PhosphoSitePlus
T1161 Phosphorylation PhosphoSitePlus
S1162 Phosphorylation PhosphoSitePlus
S1185 Phosphorylation PhosphoSitePlus
T1186 Phosphorylation PhosphoSitePlus
T1192 Phosphorylation PhosphoSitePlus
K1223 Ubiquitination PhosphoSitePlus
K1251 Ubiquitination PhosphoSitePlus
S1261 Phosphorylation PhosphoSitePlus
K1264 Ubiquitination PhosphoSitePlus
T1265 Phosphorylation HPRD 20068231
S1278 Phosphorylation PhosphoSitePlus
T1286 Phosphorylation PhosphoSitePlus
S1288 Phosphorylation PhosphoSitePlus
S1292 Phosphorylation PhosphoSitePlus
S1303 Phosphorylation PhosphoSitePlus
S1306 Phosphorylation PhosphoSitePlus
T1313 Phosphorylation PhosphoSitePlus
Y1351 Phosphorylation PhosphoSitePlus
S1366 Phosphorylation PhosphoSitePlus
S1370 Phosphorylation PhosphoSitePlus
T1377 Phosphorylation PhosphoSitePlus
Y1379 Phosphorylation PhosphoSitePlus
T1381 Phosphorylation PhosphoSitePlus
T1387 Phosphorylation HPRD   PhosphoSitePlus 20068231
K1394 Acetylation PhosphoSitePlus
K1395 Acetylation PhosphoSitePlus
K1396 Acetylation PhosphoSitePlus
S1413 Phosphorylation PhosphoSitePlus
T1421 Phosphorylation PhosphoSitePlus
Y1464 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T1467 Phosphorylation PhosphoSitePlus
S1478 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S1480 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S1482 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T1483 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S1514 Phosphorylation PhosphoSitePlus
T1517 Phosphorylation PhosphoSitePlus
S1574 Phosphorylation PhosphoSitePlus
S1600 Phosphorylation PhosphoSitePlus
S1603 Phosphorylation PhosphoSitePlus
T1604 Phosphorylation PhosphoSitePlus
S1714 Phosphorylation HPRD   PhosphoSitePlus 20068231
T1722 Phosphorylation PhosphoSitePlus
T1725 Phosphorylation PhosphoSitePlus
S1726 Phosphorylation PhosphoSitePlus
T1730 Phosphorylation PhosphoSitePlus
K1731 Acetylation PhosphoSitePlus
S1739 Phosphorylation PhosphoSitePlus
T1764 Phosphorylation PhosphoSitePlus
K1774 Acetylation PhosphoSitePlus
K1788 Acetylation PhosphoSitePlus
K1795 Acetylation PhosphoSitePlus
K1813 Ubiquitination PhosphoSitePlus
K1814 Ubiquitination PhosphoSitePlus
T1855 Phosphorylation PhosphoSitePlus
Y1856 Phosphorylation PhosphoSitePlus
K1863 Acetylation PhosphoSitePlus
S1919 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T69 S69 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y195 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K249 E249 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y269 H269 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T381 M381 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
Y424 C424 Biomuta DOID:1324 / lung cancer [ icgc ]
K505 T505 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T607 N607 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y719 C719 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S742 T742 Biomuta DOID:1612 / breast cancer [ cosmic ]
T790 M790 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
S952 L952 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T964 I964 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T997 I997 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
K1046 N1046 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ]
K1097 M1097 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K1111 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K1113 N1113 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S1144 F1144 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T1161 P1161 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1185 Y1185 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T1192 K1192 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1192 M1192 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K1223 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K1264 R1264 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1288 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1292 L1292 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1303 Y1303 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1306 F1306 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1366 C1366 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
T1381 M1381 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T1467 I1467 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1478 L1478 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1478 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S1574 F1574 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1739 F1739 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1788 N1788 Biomuta DOID:1612 / breast cancer [ cosmic ]
K1813 Q1813 Biomuta DOID:3571 / liver cancer [ cosmic, icgc, tcga ]
S1919 T1919 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]