Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y617 / SERC_HUMAN
Protein Name Phosphoserine aminotransferase
Gene Name Name: PSAT1
Synonyms:PSA;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y617
DAG View
PRO Name phosphoserine aminotransferase (human)
Definition A phosphoserine aminotransferase that is encoded in the genome of human.
Short Label hPSAT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y617 (PSAT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
R5 Methylation PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
Y32 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
R45 Methylation PhosphoSitePlus
K51 Acetylation PhosphoSitePlus   UniProt 19608861
K51 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
R97 Methylation PhosphoSitePlus
C98 S-Nitrosylation dbSNO 26338901
K110 Acetylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K117 Acetylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
K127 Acetylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
R222 Methylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
K269 Acetylation PhosphoSitePlus   UniProt 19608861
K269 Ubiquitination PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
Y279 Phosphorylation PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
K311 Acetylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K318 Acetylation PhosphoSitePlus   UniProt 19608861
K318 Ubiquitination PhosphoSitePlus
K323 Acetylation PhosphoSitePlus   UniProt 19608861
K323 Ubiquitination PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus   UniProt 23186163
K333 Acetylation PhosphoSitePlus   UniProt 19608861
K333 Methylation PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
R336 Methylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
Y346 Phosphorylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K363 Acetylation PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S178 Phosphorylation HPRD 20068231
S179 Phosphorylation HPRD 20068231
S331 Phosphorylation HPRD 20068231
S344 Phosphorylation HPRD 19664994
Y346 Phosphorylation HPRD 17322306
Site PTM Type PTM Enzyme Score Source PMID
S178 Phosphorylation HPRD 20068231
S179 Phosphorylation HPRD 20068231
S298 Phosphorylation HPRD 19664994
Y300 Phosphorylation HPRD 17322306


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S20 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
K94 E94 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K110 Q110 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc, tcga ]
R222 Q222 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ] DOID:3070 / malignant glioma [ tcga ]
K269 N269 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K318 N318 Biomuta DOID:363 / uterine cancer [ tcga ]
K363 N363 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]