Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y613 / FHOD1_HUMAN
Protein Name FH1/FH2 domain-containing protein 1
Gene Name Name: FHOD1
Synonyms:FHOS,FHOS1;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y613
DAG View
PRO Name FH1/FH2 domain-containing protein 1 (human)
Definition An FH1/FH2 domain-containing protein 1 that is encoded in the genome of human.
Short Label hFHOD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y613 (FHOD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C31 S-Nitrosylation dbSNO 26338901
Y99 Phosphorylation P12931 (SRC) PhosphoSitePlus 24331927
K126 Ubiquitination PhosphoSitePlus
Y176 Phosphorylation PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
S367 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18088087, 15302935, ...18669648, 20068231
Y439 Phosphorylation PhosphoSitePlus
T465 Phosphorylation PhosphoSitePlus
S486 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 23186163
T489 Phosphorylation PhosphoSitePlus
T495 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 18088087
S498 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 18088087, ...18220336, 18767875, 17322306, 18669648, 23186163
S510 Phosphorylation PhosphoSitePlus
S523 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18088087, 20058876, ...19413330, 18669648, 23186163, 20068231
K525 Ubiquitination PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
S573 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 24275569
K635 Methylation PhosphoSitePlus
K676 Ubiquitination PhosphoSitePlus
S681 Phosphorylation PhosphoSitePlus
T690 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 23186163
S700 Phosphorylation PhosphoSitePlus
T708 Phosphorylation PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
T816 Phosphorylation PhosphoSitePlus
T823 Phosphorylation HPRD   PhosphoSitePlus 18452278
K851 Ubiquitination PhosphoSitePlus
S874 Phosphorylation PhosphoSitePlus
Y878 Phosphorylation PhosphoSitePlus
K889 Ubiquitination PhosphoSitePlus
K918 Ubiquitination PhosphoSitePlus
Y960 Phosphorylation PhosphoSitePlus
Y963 Phosphorylation PhosphoSitePlus
K1000 Ubiquitination PhosphoSitePlus
T1010 Phosphorylation PhosphoSitePlus
R1044 Methylation PhosphoSitePlus
T1103 Phosphorylation PhosphoSitePlus
S1114 Phosphorylation PhosphoSitePlus
S1131 Phosphorylation Q13464 (ROCK1) , Q13976 (PRKG1) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 18239683, 15051728, 21106951
S1137 Phosphorylation Q13464 (ROCK1) PhosphoSitePlus   RLIMS-P   Signor 18239683
T1141 Phosphorylation Q13464 (ROCK1) PhosphoSitePlus   RLIMS-P   Signor 18239683, 21106951
S1144 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y176 * Biomuta DOID:3571 / liver cancer [ icgc ]
S367 Y367 Biomuta DOID:1909 / melanoma [ cosmic ]
T465 K465 Biomuta DOID:3571 / liver cancer [ icgc ]
S486 C486 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S573 * Biomuta DOID:11934 / head and neck cancer [ tcga ]
T690 K690 Biomuta DOID:3571 / liver cancer [ icgc ]
S700 R700 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K851 N851 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
Y960 * Biomuta DOID:3571 / liver cancer [ icgc ]
R1044 Q1044 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
R1044 W1044 Biomuta DOID:1909 / melanoma [ cosmic ]
T1103 I1103 Biomuta DOID:3571 / liver cancer [ tcga ]
T1141 M1141 Biomuta DOID:11054 / urinary bladder cancer [ icgc, tcga ]