iPTMnet Report for Q9Y5Z7 (HCFC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y5Z7 / HCFC2_HUMAN
Protein Name Host cell factor 2
Gene Name Name: HCFC2
Organism Homo sapiens (Human)

PRO ID PR:Q9Y5Z7
DAG View
PRO Name host cell factor 2 (human)
Definition A host cell factor 2 that is encoded in the genome of human.
Short Label hHCFC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y5Z7 (HCFC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation PhosphoSitePlus
Y159 Phosphorylation PhosphoSitePlus
K207 Acetylation PhosphoSitePlus
T237 Phosphorylation PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
S514 O-Glycosylation GlyGen 31492838, 35132862, 34019948
Y560 Phosphorylation PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
K771 Acetylation PhosphoSitePlus
K771 Ubiquitination PhosphoSitePlus
K788 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S246 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T237 N237 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S246 N246 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]