iPTMnet Report for Q9Y5Y9 (SCN10A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y5Y9 / SCNAA_HUMAN
Protein Name Sodium channel protein type 10 subunit alpha
Gene Name Name: SCN10A
Organism Homo sapiens (Human)

PRO ID PR:Q9Y5Y9
DAG View
PRO Name sodium channel protein type 10 subunit alpha (human)
Definition A sodium channel protein type 10 subunit alpha that is encoded in the genome of human.
Short Label hSCN10A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y5Y9 (SCN10A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T91 Phosphorylation PhosphoSitePlus
T100 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
S552 Phosphorylation neXtProt 18354022
S552 Phosphorylation Q16539 (MAPK14) neXtProt 18354022
Y723 Phosphorylation PhosphoSitePlus
Y724 Phosphorylation PhosphoSitePlus
S930 Phosphorylation PhosphoSitePlus
S933 Phosphorylation PhosphoSitePlus
K957 Ubiquitination PhosphoSitePlus
Y1188 Phosphorylation PhosphoSitePlus
Y1208 Phosphorylation PhosphoSitePlus
K1441 Acetylation PhosphoSitePlus
S1451 Phosphorylation neXtProt 22426212
S1451 Phosphorylation Q02156 (PRKCE) neXtProt 22426212
T1497 Phosphorylation PhosphoSitePlus
S1838 Phosphorylation PhosphoSitePlus
Y1839 Phosphorylation PhosphoSitePlus
Y1862 Phosphorylation PhosphoSitePlus
T1925 Phosphorylation PhosphoSitePlus
S1929 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T100 I100 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S488 F488 Biomuta DOID:4159 / skin cancer [ cosmic ]
S930 G930 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y1208 C1208 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S1451 F1451 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1838 F1838 Biomuta DOID:4159 / skin cancer [ cosmic ]