Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y5Q9 / TF3C3_HUMAN
Protein Name General transcription factor 3C polypeptide 3
Gene Name Name: GTF3C3
Organism Homo sapiens (Human)

PRO ID PR:Q9Y5Q9
DAG View
PRO Name general transcription factor 3C polypeptide 3 (human)
Definition A general transcription factor 3C polypeptide 3 that is encoded in the genome of human.
Short Label hGTF3C3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y5Q9 (GTF3C3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22223895
S5 Phosphorylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
S43 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...19690332
S51 Phosphorylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
R150 Methylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
T188 Phosphorylation PhosphoSitePlus
K234 Sumoylation PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
Y246 Phosphorylation PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
R275 Methylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus   UniProt 23186163
S284 Phosphorylation PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
K359 Ubiquitination PhosphoSitePlus
T366 Phosphorylation PhosphoSitePlus
T377 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
Y471 Phosphorylation PhosphoSitePlus
K481 Ubiquitination PhosphoSitePlus
S495 Phosphorylation PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus
K508 Ubiquitination PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
K580 Ubiquitination PhosphoSitePlus
K590 Ubiquitination PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
K595 Ubiquitination PhosphoSitePlus
Y686 Phosphorylation PhosphoSitePlus
K699 Sumoylation PhosphoSitePlus
K728 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S43 Phosphorylation HPRD 19413330, 19664995, 18452278, ...19651622, 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 L2 Biomuta DOID:1612 / breast cancer [ tcga ]
S43 * Biomuta DOID:1612 / breast cancer [ tcga ] DOID:11054 / urinary bladder cancer [ tcga ]
K80 R80 Biomuta DOID:11934 / head and neck cancer [ tcga ]
R150 K150 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K242 Q242 Biomuta DOID:363 / uterine cancer [ tcga ]
S282 Y282 Biomuta DOID:3571 / liver cancer [ icgc ]
K699 I699 Biomuta DOID:3571 / liver cancer [ icgc ]