iPTMnet Report for Q9Y5N6 (ORC6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y5N6 / ORC6_HUMAN
Protein Name Origin recognition complex subunit 6
Gene Name Name: ORC6
Synonyms:ORC6L;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y5N6
DAG View
PRO Name origin recognition complex subunit 6 (human)
Definition An origin recognition complex subunit 6 that is encoded in the genome of human.
Short Label hORC6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y5N6 (ORC6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K23 Ubiquitination PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
C35 Methylation IEDB 31844290
R65 Methylation PhosphoSitePlus
Y67 Phosphorylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
T78 Phosphorylation PhosphoSitePlus
Y79 Phosphorylation PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
C149 Methylation IEDB 31844290
K168 Acetylation PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
T195 Phosphorylation P06493 (CDK1) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 17081983, ...18234856, 19664994, 19664995, 18452278, 18669648, 20068231
K202 Ubiquitination PhosphoSitePlus
K210 Acetylation PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K214 Acetylation PhosphoSitePlus
K221 Acetylation PhosphoSitePlus
T229 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17525332
Y232 Phosphorylation PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C35 W35 Biomuta DOID:1324 / lung cancer [ cosmic ]
K181 N181 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K210 N210 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K248 N248 Biomuta DOID:363 / uterine cancer [ icgc ]