iPTMnet Report for Q9Y5M8 (SRPRB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y5M8 / SRPRB_HUMAN
Protein Name Signal recognition particle receptor subunit beta
Gene Name Name: SRPRB
ORFNames:PSEC0230;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y5M8
DAG View
PRO Name signal recognition particle receptor subunit beta (human)
Definition A signal recognition particle receptor subunit beta that is encoded in the genome of human.
Short Label hSRPRB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y5M8 (SRPRB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T18 O-Glycosylation GlyGen 33214551, 25813380, 35132862, ...35083852, 34931806, 33465208, 29237092
R109 Methylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus   UniProt 23186163
T114 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K199 Acetylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
S213 O-Glycosylation GlyGen 33465208
T214 Phosphorylation PhosphoSitePlus   UniProt 23186163
S217 O-Glycosylation GlyGen 33465208
S217 Phosphorylation PhosphoSitePlus
S218 O-Glycosylation GlyGen 33214551, 35132862, 35083852, ...34931806, 33465208, 29237092
S218 Phosphorylation PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
S247 Phosphorylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T18 P18 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R109 K109 Biomuta [ cosmic ]
T114 N114 Biomuta DOID:363 / uterine cancer [ icgc ]
S218 Y218 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K249 N249 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]