Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y5K5 / UCHL5_HUMAN
Protein Name Ubiquitin carboxyl-terminal hydrolase isozyme L5
Gene Name Name: UCHL5
Synonyms:UCH37;ORFNames:AD-019,CGI-70;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y5K5
DAG View
PRO Name ubiquitin carboxyl-terminal hydrolase isozyme L5 (human)
Definition A ubiquitin carboxyl-terminal hydrolase isozyme L5 that is encoded in the genome of human.
Short Label hUCHL5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y5K5 (UCHL5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K45 Ubiquitination PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
K154 Sumoylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
K158 Acetylation PhosphoSitePlus   UniProt 19608861
K158 Ubiquitination PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
R227 Methylation PhosphoSitePlus
K228 Acetylation PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S254 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K314 Ubiquitination PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K277 T277 Biomuta DOID:363 / uterine cancer [ tcga ]
K282 * Biomuta DOID:1324 / lung cancer [ tcga ]
K301 N301 Biomuta DOID:363 / uterine cancer [ tcga ]
K317 N317 Biomuta DOID:3070 / malignant glioma [ tcga ]