iPTMnet Report for Q9Y5K3 (PCYT1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y5K3 / PCY1B_HUMAN
Protein Name Choline-phosphate cytidylyltransferase B
Gene Name Name: PCYT1B
Synonyms:CCTB;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y5K3
DAG View
PRO Name choline-phosphate cytidylyltransferase B (human)
Definition A choline-phosphate cytidylyltransferase B that is encoded in the genome of human.
Short Label hPCYT1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y5K3 (PCYT1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T71 Phosphorylation PhosphoSitePlus
Y173 Phosphorylation PhosphoSitePlus
Y182 Phosphorylation PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
T197 Phosphorylation PhosphoSitePlus
Y216 Phosphorylation PhosphoSitePlus
K228 Acetylation PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
S233 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K254 Ubiquitination PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
S315 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935, 21406692
S319 Phosphorylation PhosphoSitePlus   UniProt 21406692
S322 Phosphorylation PhosphoSitePlus
T325 Phosphorylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
T345 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus   UniProt 21406692
Site PTM Type PTM Enzyme Score Source PMID
S233 Phosphorylation HPRD 18669648, 20068231
S271 Phosphorylation HPRD 18452278
S315 Phosphorylation HPRD 17322306, 18691976, 18669648, ...19664994, 20068231
S319 Phosphorylation HPRD 15345747, 20068231
T325 Phosphorylation HPRD 15345747
S335 Phosphorylation HPRD 19664995
Site PTM Type PTM Enzyme Score Source PMID
T33 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K228 N228 Biomuta DOID:363 / uterine cancer [ icgc ]
S271 G271 Biomuta DOID:263 / kidney cancer [ cosmic ]
S319 I319 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T345 I345 Biomuta DOID:9256 / colorectal cancer [ cosmic ]