iPTMnet Report for Q9Y5J1 (UTP18)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y5J1 / UTP18_HUMAN
Protein Name U3 small nucleolar RNA-associated protein 18 homolog
Gene Name Name: UTP18
Synonyms:WDR50;ORFNames:CDABP0061,CGI-48;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y5J1
DAG View
PRO Name U3 small nucleolar RNA-associated protein 18 homolog (human)
Definition A U3 small nucleolar RNA-associated protein 18 that is encoded in the genome of human.
Short Label hUTP18
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y5J1 (UTP18) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K41 Ubiquitination PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus
K84 Sumoylation PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
S121 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19691289, 21406692, 18491316, ...23186163, 17081983, 15302935, 19007248, 18318008, 19651622, 19367720, 18669648, 24275569, 20166139, 17287340, 18452278, 19415658, 20068231, 16964243
S124 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19691289, 21406692, 16083285, ...17287340, 16964243, 15302935, 19007248, 18452278, 19651622, 19367720, 18669648, 18491316, 24275569, 20166139, 23186163, 18318008, 19415658, 20068231, 17081983
K172 Sumoylation PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
K175 Sumoylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K183 Sumoylation PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
T204 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 18452278, ...18669648, 24275569, 20166139, 19415658, 20068231
S205 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 16565220, 19651622, ...18669648, 20166139, 18452278, 19415658, 20068231
S206 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 17081983, ...18452278, 19651622, 18669648, 19690332, 20166139, 16565220, 19415658
S210 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...17081983, 18767875, 19691289, 18452278, 19651622, 18669648, 19690332, 24275569, 20166139, 16565220, 19415658, 20068231
T221 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19691289
S226 Phosphorylation HPRD 20068231
S230 Phosphorylation HPRD 20068231
K239 Ubiquitination PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
S290 Phosphorylation HPRD 20068231
Y292 Phosphorylation PhosphoSitePlus
C302 Methylation IEDB 31844290
Y321 Phosphorylation PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus
Y364 Phosphorylation PhosphoSitePlus
T372 Phosphorylation PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
S425 O-Glycosylation GlyGen 28510447, 33465208
Y427 Phosphorylation PhosphoSitePlus
C507 Methylation IEDB 31844290
K517 Ubiquitination PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
S530 Phosphorylation PhosphoSitePlus
Y535 Phosphorylation PhosphoSitePlus
K542 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S45 L45 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S290 N290 Biomuta DOID:4159 / skin cancer [ cosmic ]
T372 N372 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K519 N519 Biomuta DOID:363 / uterine cancer [ icgc ]