iPTMnet Report Q9Y5C1 ANGPTL3

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q9Y5C1 / ANGL3_HUMAN
Protein Name	Angiopoietin-related protein 3 precursor
Gene Name	Name: ANGPTL3 Synonyms:ANGPT5;ORFNames:UNQ153/PRO179;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9Y5C1 DAG View
PRO Name	angiopoietin-related protein 3 (human)
Definition	An angiopoietin-related protein 3 that is encoded in the genome of human.
Short Label	hANGPTL3
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9Y5C1 (ANGPTL3) as Substrate

Q9Y5C1

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N23	N-Glycosylation		score1	GlyGen	30237853
	S25	Phosphorylation		score0	HPRD	19824718
	N115	N-Glycosylation		score4	GlyGen UniProt	16335952, 29741879, 10644446
	S122	O-Glycosylation		score1	GlyGen	29351928
	T206	Phosphorylation		score1	PhosphoSitePlus
	S207	Phosphorylation		score1	PhosphoSitePlus
	T212	O-Glycosylation		score1	GlyGen	30459171
	T225	O-Glycosylation		score1	GlyGen	30459171
	T226	O-Glycosylation		score3	GlyGen UniProt	20837471
	N296	N-Glycosylation		score2	GlyGen UniProt	16335952, 23090970, 30237853, ...19159218, 24190977
	N357	N-Glycosylation		score2	GlyGen UniProt	16335952
	S436	Phosphorylation		score1	PhosphoSitePlus
	S446	Phosphorylation		score1	PhosphoSitePlus
	T447	Phosphorylation		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
N115	K115	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
S122	*	Biomuta		DOID:5041 / esophageal cancer [ cosmic ]
N296	K296	Biomuta		DOID:4159 / skin cancer [ cosmic ]