iPTMnet Report for Q9Y5B0 (CTDP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y5B0 / CTDP1_HUMAN
Protein Name RNA polymerase II subunit A C-terminal domain phosphatase
Gene Name Name: CTDP1
Synonyms:FCP1;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y5B0
DAG View
PRO Name RNA polymerase II subunit A C-terminal domain phosphatase (human)
Definition An RNA polymerase II subunit A C-terminal domain phosphatase that is encoded in the genome of human.
Short Label hCTDP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y5B0 (CTDP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S162 Phosphorylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
Y240 Phosphorylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus   RLIMS-P 31240132
T340 Phosphorylation PhosphoSitePlus   RLIMS-P 31240132
T391 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus   UniProt 23186163
S471 Phosphorylation PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
S575 Phosphorylation P67870 (CSNK2B) , P68400 (CSNK2A1) , P19784 (CSNK2A2) phospho.ELM   PhosphoSitePlus   Signor 12591939
T584 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 15723518
K607 Ubiquitination PhosphoSitePlus
K614 Acetylation PhosphoSitePlus
K614 Ubiquitination PhosphoSitePlus
K624 Ubiquitination PhosphoSitePlus
K630 Ubiquitination PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus
K653 Ubiquitination PhosphoSitePlus
T654 Phosphorylation IEDB 35494241
K666 Ubiquitination PhosphoSitePlus
S674 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243, ...20068231
K720 Ubiquitination PhosphoSitePlus
K734 Ubiquitination PhosphoSitePlus
S740 Phosphorylation P19784 (CSNK2A2) , P68400 (CSNK2A1) , P67870 (CSNK2B) phospho.ELM   PhosphoSitePlus   Signor   UniProt 23186163, 16964243, 15302935, ...18669648, 12591939
Y774 Phosphorylation PhosphoSitePlus
K780 Acetylation PhosphoSitePlus   UniProt 19608861
K780 Ubiquitination PhosphoSitePlus
S793 O-Glycosylation GlyGen 31373491
S794 O-Glycosylation GlyGen 31373491
S795 O-Glycosylation GlyGen 31373491
S839 Phosphorylation PhosphoSitePlus   UniProt 23186163
S841 Phosphorylation PhosphoSitePlus
T843 Phosphorylation PhosphoSitePlus
Y847 Phosphorylation PhosphoSitePlus
S856 Phosphorylation PhosphoSitePlus
S869 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 20068231
S872 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 20068231
S874 Phosphorylation PhosphoSitePlus
R913 Methylation PhosphoSitePlus
R916 Methylation PhosphoSitePlus
S935 Phosphorylation PhosphoSitePlus
S936 Phosphorylation PhosphoSitePlus
S942 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 15723518
S943 Phosphorylation PhosphoSitePlus
S944 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 15723518
Site PTM Type PTM Enzyme Score Source PMID
S575 Phosphorylation P19784 (CSNK2A2) , P68400 (CSNK2A1) , P67870 (CSNK2B) HPRD 12591939
S631 Phosphorylation HPRD 18452278
S674 Phosphorylation HPRD 18669648, 20068231
S740 Phosphorylation P67870 (CSNK2B) , P19784 (CSNK2A2) , P68400 (CSNK2A1) HPRD 12591939, 18669648, 19664994, ...19664995
S869 Phosphorylation HPRD 19651622, 17081983, 20068231
S872 Phosphorylation HPRD 17322306, 19651622, 20068231
S874 Phosphorylation HPRD 18767875
Site PTM Type PTM Enzyme Score Source PMID
S575 Phosphorylation P19784 (CSNK2A2) , P68400 (CSNK2A1) , P67870 (CSNK2B) HPRD 12591939
S631 Phosphorylation HPRD 18452278
S674 Phosphorylation HPRD 18669648, 20068231
S740 Phosphorylation P19784 (CSNK2A2) , P67870 (CSNK2B) , P68400 (CSNK2A1) HPRD 12591939, 18669648, 19664994, ...19664995
S831 Phosphorylation PhosphoSitePlus
S833 Phosphorylation PhosphoSitePlus
S836 Phosphorylation PhosphoSitePlus
S842 Phosphorylation PhosphoSitePlus
R865 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T340 M340 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T584 M584 Biomuta DOID:1612 / breast cancer [ cosmic ]
T654 M654 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K780 M780 Biomuta DOID:263 / kidney cancer [ cosmic ]
S793 F793 Biomuta DOID:4159 / skin cancer [ cosmic ]
S841 Y841 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y847 H847 Biomuta DOID:263 / kidney cancer [ cosmic ]
S856 N856 Biomuta DOID:263 / kidney cancer [ cosmic ]
S872 I872 Biomuta DOID:363 / uterine cancer [ cosmic ]
S874 R874 Biomuta DOID:3571 / liver cancer [ cosmic ]
R913 W913 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S942 R942 Biomuta DOID:1324 / lung cancer [ cosmic ]