iPTMnet Report for Q9Y597 (KCTD3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y597 / KCTD3_HUMAN
Protein Name BTB/POZ domain-containing protein KCTD3
Gene Name Name: KCTD3
Organism Homo sapiens (Human)

PRO ID PR:Q9Y597
DAG View
PRO Name BTB/POZ domain-containing protein KCTD3 (human)
Definition A BTB/POZ domain-containing protein KCTD3 that is encoded in the genome of human.
Short Label hKCTD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y597 (KCTD3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T35 Phosphorylation PhosphoSitePlus
T54 Phosphorylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
R86 Methylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
K426 Ubiquitination PhosphoSitePlus
T463 Phosphorylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
K503 Ubiquitination PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus
T588 Phosphorylation PhosphoSitePlus
K594 Ubiquitination PhosphoSitePlus
T603 Phosphorylation PhosphoSitePlus
S604 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T608 Phosphorylation PhosphoSitePlus
S612 Phosphorylation PhosphoSitePlus
T615 Phosphorylation PhosphoSitePlus
Y650 Phosphorylation PhosphoSitePlus
S653 Phosphorylation PhosphoSitePlus
T662 Phosphorylation PhosphoSitePlus
S664 Phosphorylation PhosphoSitePlus   UniProt 23186163
S667 Phosphorylation PhosphoSitePlus
S711 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S736 Phosphorylation PhosphoSitePlus
K739 Acetylation PhosphoSitePlus
S743 Phosphorylation PhosphoSitePlus
K750 Methylation PhosphoSitePlus
K750 Ubiquitination PhosphoSitePlus
S776 Phosphorylation PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus
S791 Phosphorylation PhosphoSitePlus
S793 Phosphorylation PhosphoSitePlus   UniProt 23186163
T798 Phosphorylation PhosphoSitePlus
S800 Phosphorylation PhosphoSitePlus
S806 Phosphorylation PhosphoSitePlus
S808 Phosphorylation PhosphoSitePlus
S809 Phosphorylation PhosphoSitePlus
S814 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T588 Phosphorylation HPRD 20068231
S604 Phosphorylation HPRD 18669648
S711 Phosphorylation HPRD 18669648, 20068231
S793 Phosphorylation HPRD 20068231
T795 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K81 E81 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S148 F148 Biomuta DOID:4159 / skin cancer [ cosmic ]
K237 N237 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K237 Q237 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K582 R582 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K582 M582 Biomuta DOID:4159 / skin cancer [ cosmic ]
K582 N582 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S653 G653 Biomuta DOID:3571 / liver cancer [ cosmic ]
S736 L736 Biomuta DOID:4159 / skin cancer [ cosmic ]
K739 R739 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S743 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S806 G806 Biomuta DOID:10534 / stomach cancer [ cosmic ]