iPTMnet Report for Q9Y573 (IPP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y573 / IPP_HUMAN
Protein Name Actin-binding protein IPP
Gene Name Name: IPP
Synonyms:KLHL27;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y573
DAG View
PRO Name actin-binding protein IPP (human)
Definition An actin-binding protein IPP that is encoded in the genome of human.
Short Label hIPP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y573 (IPP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K8 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
Y239 Phosphorylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
Y289 Phosphorylation PhosphoSitePlus
Y291 Phosphorylation PhosphoSitePlus
Y296 Phosphorylation PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus
K463 Ubiquitination PhosphoSitePlus
C486 Methylation IEDB 31844290
K520 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K185 I185 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K264 R264 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
S265 C265 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K270 T270 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y296 H296 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K463 N463 Biomuta DOID:184 / bone cancer [ cosmic ]