iPTMnet Report for Q9Y561 (LRP12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y561 / LRP12_HUMAN
Protein Name Low-density lipoprotein receptor-related protein 12 precursor
Gene Name Name: LRP12
Synonyms:ST7;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y561
DAG View
PRO Name low-density lipoprotein receptor-related protein 12 (human)
Definition A low-density lipoprotein receptor-related protein 12 that is encoded in the genome of human.
Short Label hLRP12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y561 (LRP12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
T7 Phosphorylation PhosphoSitePlus
N75 N-Glycosylation GlyGen 23090970, 24190977
K160 Ubiquitination PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
C395 Methylation IEDB 31844290
K415 Ubiquitination PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
R432 Methylation PhosphoSitePlus
Y435 Phosphorylation PhosphoSitePlus
T495 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
T515 Phosphorylation PhosphoSitePlus
S584 Phosphorylation PhosphoSitePlus
T589 Phosphorylation PhosphoSitePlus
S617 Phosphorylation PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
T655 Phosphorylation PhosphoSitePlus
T657 Phosphorylation PhosphoSitePlus
K678 Ubiquitination PhosphoSitePlus
S720 Phosphorylation PhosphoSitePlus
S749 Phosphorylation PhosphoSitePlus
S755 Phosphorylation PhosphoSitePlus
S851 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T495 Phosphorylation HPRD 20166139
S501 Phosphorylation HPRD 20166139
T515 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N75 T75 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K228 R228 Biomuta DOID:3571 / liver cancer [ cosmic ]
K305 I305 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
C395 Y395 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R432 C432 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
R432 G432 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y435 C435 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S631 N631 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T657 A657 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K678 N678 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S749 F749 Biomuta DOID:9256 / colorectal cancer [ cosmic ]