iPTMnet Report for Q9Y546 (LRRC42)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y546 / LRC42_HUMAN
Protein Name Leucine-rich repeat-containing protein 42
Gene Name Name: LRRC42
Organism Homo sapiens (Human)

PRO ID PR:Q9Y546
DAG View
PRO Name leucine-rich repeat-containing protein 42 (human)
Definition A leucine-rich repeat-containing protein 42 that is encoded in the genome of human.
Short Label hLRRC42
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y546 (LRRC42) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S36 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K220 Sumoylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
K349 Methylation PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
C373 Methylation IEDB 31844290
K379 Acetylation PhosphoSitePlus
K379 Sumoylation PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K389 Ubiquitination PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
S407 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17525332
K411 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K40 N40 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S52 F52 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K140 Q140 Biomuta DOID:1793 / pancreatic cancer [ icgc ]