Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y508 / RN114_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF114
Gene Name Name: RNF114
Synonyms:ZNF228,ZNF313;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y508
DAG View
PRO Name E3 ubiquitin-protein ligase RNF114 (human)
Definition An E3 ubiquitin-protein ligase RNF114 that is encoded in the genome of human.
Short Label hRNF114
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y508 (RNF114) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K38 Ubiquitination PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K102 Acetylation PhosphoSitePlus   UniProt 19608861
K102 Sumoylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
K112 Acetylation PhosphoSitePlus   UniProt 19608861
K112 Ubiquitination PhosphoSitePlus
Y116 Phosphorylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K126 Sumoylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
Y186 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
Y203 Phosphorylation PhosphoSitePlus
Y209 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K61 N61 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ] DOID:3571 / liver cancer [ icgc ]