iPTMnet Report for Q9Y4Z0 (LSM4)
Protein Information
| UniProt AC / UniProt ID | Q9Y4Z0 / LSM4_HUMAN |
| Protein Name | U6 snRNA-associated Sm-like protein LSm4 |
| Gene Name | Name: LSM4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y4Z0 |
| PRO Name | U6 snRNA-associated Sm-like protein LSm4 (human) |
| Definition | A U6 snRNA-associated Sm-like protein LSm4 that is encoded in the genome of human. |
| Short Label | hLSM4 |
| Category | organism-gene |
Q9Y4Z0 (LSM4) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| C32 | Methylation | score1 | IEDB | 31844290 | ||
| K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C59 | S-Nitrosylation | score0 | dbSNO | 24105792 | ||
| R62 | Methylation | score1 | PhosphoSitePlus | |||
| K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R88 | Methylation | score1 | PhosphoSitePlus | |||
| R90 | Methylation | score1 | PhosphoSitePlus | |||
| R102 | Methylation | score1 | PhosphoSitePlus | |||
| R109 | Methylation | score1 | PhosphoSitePlus | |||
| R115 | Methylation | score1 | PhosphoSitePlus | |||
| R117 | Methylation | score1 | PhosphoSitePlus | |||
| R125 | Methylation | score1 | PhosphoSitePlus | |||
| K138 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R88 | C88 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R88 | H88 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R90 | C90 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R109 | L109 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
| R109 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| R115 | W115 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View