iPTMnet Report for Q9Y4X5 (ARIH1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y4X5 / ARI1_HUMAN
Protein Name E3 ubiquitin-protein ligase ARIH1
Gene Name Name: ARIH1
Synonyms:ARI,MOP6;ORFNames:HUSSY-27;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y4X5
DAG View
PRO Name E3 ubiquitin-protein ligase ARIH1 (human)
Definition An E3 ubiquitin-protein ligase ARIH1 that is encoded in the genome of human.
Short Label hARIH1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y4X5 (ARIH1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K142 Acetylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
Y197 Phosphorylation PhosphoSitePlus
T199 Phosphorylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
K368 Ubiquitination PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
K439 Ubiquitination PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S196 L196 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S196 W196 Biomuta [ cosmic ]
S517 C517 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S517 Y517 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]