Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y4X4 / KLF12_HUMAN
Protein Name Krueppel-like factor 12
Gene Name Name: KLF12
Synonyms:AP2REP;ORFNames:HSPC122;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y4X4
DAG View
PRO Name krueppel-like factor 12 (human)
Definition A krueppel-like factor 12 that is encoded in the genome of human.
Short Label hKLF12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y4X4 (KLF12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T15 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
T91 Phosphorylation PhosphoSitePlus
S92 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
T104 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
T209 Phosphorylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
K313 Methylation PhosphoSitePlus   UniProt 18438403
T340 Phosphorylation PhosphoSitePlus
T342 Phosphorylation PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T15 I15 Biomuta DOID:1612 / breast cancer [ tcga ]
S42 Y42 Biomuta DOID:363 / uterine cancer [ tcga ]
T91 M91 Biomuta DOID:363 / uterine cancer [ tcga ]
S92 F92 Biomuta DOID:1324 / lung cancer [ tcga ]
S102 F102 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T104 K104 Biomuta DOID:3571 / liver cancer [ icgc ]
S240 N240 Biomuta DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]
S240 I240 Biomuta DOID:363 / uterine cancer [ tcga ]
S293 L293 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ]
K313 R313 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]