iPTMnet Report for Q9Y4W6 (AFG3L2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y4W6 / AFG32_HUMAN
Protein Name AFG3-like protein 2 precursor
Gene Name Name: AFG3L2
Organism Homo sapiens (Human)

PRO ID PR:Q9Y4W6
DAG View
PRO Name AFG3-like protein 2 (human)
Definition An AFG3-like protein 2 that is encoded in the genome of human.
Short Label hAFG3L2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y4W6 (AFG3L2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K100 Acetylation PhosphoSitePlus
T150 Phosphorylation PhosphoSitePlus
Y160 Phosphorylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
Y179 Phosphorylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K193 Acetylation PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
T221 Phosphorylation PhosphoSitePlus
K300 Acetylation PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
K306 Acetylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
T352 Phosphorylation PhosphoSitePlus
K354 Ubiquitination PhosphoSitePlus
K481 Ubiquitination PhosphoSitePlus
S498 Phosphorylation PhosphoSitePlus
K508 Ubiquitination PhosphoSitePlus
K543 Acetylation PhosphoSitePlus
K543 Ubiquitination PhosphoSitePlus
K558 Ubiquitination PhosphoSitePlus
T560 Phosphorylation PhosphoSitePlus
K611 Ubiquitination PhosphoSitePlus
Y614 Phosphorylation PhosphoSitePlus
K618 Ubiquitination PhosphoSitePlus
R624 Methylation PhosphoSitePlus
S634 Phosphorylation PhosphoSitePlus
K710 Acetylation IEDB   PhosphoSitePlus 34357683
K738 Ubiquitination PhosphoSitePlus
T763 Phosphorylation PhosphoSitePlus
S765 Phosphorylation PhosphoSitePlus
T770 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y179 C179 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
S218 N218 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K300 N300 Biomuta DOID:1319 / brain cancer [ cosmic ]
K306 N306 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K342 N342 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T560 M560 Biomuta [ cosmic ] DOID:1612 / breast cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ]
K710 T710 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K738 N738 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ]
T763 N763 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]