iPTMnet Report for Q9Y4K3 (TRAF6)
Protein Information
| UniProt AC / UniProt ID | Q9Y4K3 / TRAF6_HUMAN |
| Protein Name | TNF receptor-associated factor 6 |
| Gene Name | Name: TRAF6 Synonyms:RNF85; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y4K3 |
| PRO Name | TNF receptor-associated factor 6 (human) |
| Definition | A TNF receptor-associated factor 6 that is encoded in the genome of human. |
| Short Label | hTRAF6 |
| Category | organism-gene |
DAG ViewQ9Y4K3 (TRAF6) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K104 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K124 | Ubiquitination | score4 | PhosphoSitePlus UniProt | 17135271, 19825828 | ||
| S188 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T266 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y288 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y326 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K331 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K365 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T486 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K489 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T492 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S507 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoform PPIs
|
Protein 1 | Relation | Protein 2 | Source | PMID |
|---|---|---|---|---|---|
| PR:000027493 (hIRAK1/iso:1/Phos:4) | Interaction | PR:Q9Y4K3 (hTRAF6) | PRO | 14625308 | |
| PR:P51617-1 (hIRAK1/iso:1) | Interaction | PR:Q9Y4K3 (hTRAF6) | PRO | 14625308 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y288 | H288 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| T492 | I492 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
