iPTMnet Report for Q9Y4K0 (LOXL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y4K0 / LOXL2_HUMAN
Protein Name Lysyl oxidase homolog 2 precursor
Gene Name Name: LOXL2
Organism Homo sapiens (Human)

PRO ID PR:Q9Y4K0
DAG View
PRO Name lysyl oxidase homolog 2 (human)
Definition A lysyl oxidase homolog 2 that is encoded in the genome of human.
Short Label hLOXL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y4K0 (LOXL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T146 Phosphorylation PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
K197 Acetylation PhosphoSitePlus
K209 Acetylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
K225 Acetylation PhosphoSitePlus
K248 Acetylation PhosphoSitePlus
N288 N-Glycosylation GlyGen 29741879
K317 Ubiquitination PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
N455 N-Glycosylation GlyGen   UniProt 24014025, 23319596
S600 Phosphorylation PhosphoSitePlus
S601 Phosphorylation PhosphoSitePlus
S609 Phosphorylation PhosphoSitePlus
N644 N-Glycosylation GlyGen   UniProt 23090970, 24014025, 23319596, ...29581294, 24190977
K759 Ubiquitination PhosphoSitePlus
S772 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T146 I146 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K225 N225 Biomuta DOID:363 / uterine cancer [ icgc ]
K225 T225 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K406 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S609 F609 Biomuta DOID:10534 / stomach cancer [ cosmic ]