iPTMnet Report for Q9Y4F9 (RIPOR2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y4F9 / RIPR2_HUMAN
Protein Name Rho family-interacting cell polarization regulator 2
Gene Name Name: RIPOR2
Synonyms:C6orf32,DIFF48,FAM65B,KIAA0386,PL48;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y4F9
DAG View
PRO Name Rho family-interacting cell polarization regulator 2 (human)
Definition A Rho family-interacting cell polarization regulator 2 that is encoded in the genome of human.
Short Label hRIPOR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y4F9 (RIPOR2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus   UniProt 25588844
S26 Phosphorylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus   UniProt 25588844
K98 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
Y223 Phosphorylation PhosphoSitePlus
Y229 Phosphorylation PhosphoSitePlus
T275 Phosphorylation IEDB 35494241
C284 Methylation IEDB 31844290
T306 Phosphorylation IEDB   PhosphoSitePlus 27869121
T314 Phosphorylation PhosphoSitePlus
Y316 Phosphorylation PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus   UniProt 25588844
Y343 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
T350 Phosphorylation PhosphoSitePlus
S389 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
S489 Phosphorylation PhosphoSitePlus
S523 Phosphorylation PhosphoSitePlus   UniProt 25588844
S524 Phosphorylation PhosphoSitePlus
S573 Phosphorylation PhosphoSitePlus
T580 Phosphorylation PhosphoSitePlus
S585 Phosphorylation PhosphoSitePlus   UniProt 25588844
S588 Phosphorylation PhosphoSitePlus
S593 Phosphorylation PhosphoSitePlus
S603 Phosphorylation PhosphoSitePlus
K623 Acetylation PhosphoSitePlus
K809 Ubiquitination PhosphoSitePlus
K848 Ubiquitination PhosphoSitePlus
S911 Phosphorylation PhosphoSitePlus
T915 Phosphorylation PhosphoSitePlus
T945 Phosphorylation PhosphoSitePlus
T951 O-Glycosylation GlyGen 30379171, 29351928
Y1043 Phosphorylation PhosphoSitePlus
K1048 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation HPRD 20058876
S21 Phosphorylation HPRD 20058876, 19664995
S341 Phosphorylation PhosphoSitePlus
Y343 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
T347 Phosphorylation PhosphoSitePlus
T350 Phosphorylation PhosphoSitePlus
T352 Phosphorylation PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S26 N26 Biomuta DOID:3565 / meningioma [ cosmic ]
S26 R26 Biomuta DOID:3571 / liver cancer [ cosmic ]
S37 F37 Biomuta DOID:4159 / skin cancer [ cosmic ]
S341 F341 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y343 F343 Biomuta DOID:1324 / lung cancer [ cosmic ]
S344 I344 Biomuta DOID:363 / uterine cancer [ cosmic ]
T350 M350 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T352 S352 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S585 T585 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]