iPTMnet Report for Q9Y4D1 (DAAM1)
Protein Information
| UniProt AC / UniProt ID | Q9Y4D1 / DAAM1_HUMAN |
| Protein Name | Disheveled-associated activator of morphogenesis 1 |
| Gene Name | Name: DAAM1 Synonyms:KIAA0666; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y4D1 |
| PRO Name | disheveled-associated activator of morphogenesis 1 (human) |
| Definition | A disheveled-associated activator of morphogenesis 1 that is encoded in the genome of human. |
| Short Label | hDAAM1 |
| Category | organism-gene |
Q9Y4D1 (DAAM1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| R9 | Methylation | score1 | PhosphoSitePlus | |||
| S12 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T27 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y28 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S34 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| K97 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K132 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K186 | Acetylation | score1 | PhosphoSitePlus | |||
| Y247 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T255 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T259 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y271 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y401 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T425 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K433 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K476 | Acetylation | score1 | PhosphoSitePlus | |||
| K489 | Acetylation | score1 | PhosphoSitePlus | |||
| K491 | Acetylation | score1 | PhosphoSitePlus | |||
| T499 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K638 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y652 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K679 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S739 | Phosphorylation | score1 | IEDB | 35494241 | ||
| K748 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S776 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S799 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S801 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y833 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K842 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y912 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1027 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
| T1061 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1074 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K657 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S12 | L12 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| S12 | P12 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| Y28 | H28 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T259 | A259 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K433 | N433 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K489 | N489 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
| K638 | N638 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S739 | G739 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S776 | L776 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
| K842 | E842 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View