iPTMnet Report for Q9Y4C2 (TCAF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y4C2 / TCAF1_HUMAN
Protein Name TRPM8 channel-associated factor 1
Gene Name Name: TCAF1
Synonyms:FAM115A,KIAA0738;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y4C2
DAG View
PRO Name TRPM8 channel-associated factor 1 (human)
Definition A TRPM8 channel-associated factor 1 that is encoded in the genome of human.
Short Label hTCAF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y4C2 (TCAF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K113 Ubiquitination PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
K369 Sumoylation PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
K439 Ubiquitination PhosphoSitePlus
C576 Methylation IEDB 31844290
K601 Ubiquitination PhosphoSitePlus
C608 Methylation IEDB 31844290
K632 Ubiquitination PhosphoSitePlus
K641 Ubiquitination PhosphoSitePlus
K651 Ubiquitination PhosphoSitePlus
K750 Ubiquitination PhosphoSitePlus
C783 Methylation IEDB 31844290
K809 Sumoylation PhosphoSitePlus
K809 Ubiquitination PhosphoSitePlus
K817 Ubiquitination PhosphoSitePlus
K865 Ubiquitination PhosphoSitePlus
S874 Phosphorylation PhosphoSitePlus
K907 Ubiquitination PhosphoSitePlus
K912 Ubiquitination PhosphoSitePlus
Y914 Phosphorylation PhosphoSitePlus
T917 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K137 N137 Biomuta DOID:1324 / lung cancer [ cosmic ]
K912 R912 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]