iPTMnet Report for Q9Y485 (DMXL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y485 / DMXL1_HUMAN
Protein Name DmX-like protein 1
Gene Name Name: DMXL1
Synonyms:XL1;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y485
DAG View
PRO Name DmX-like protein 1 (human)
Definition A DmX-like protein 1 that is encoded in the genome of human.
Short Label hDMXL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y485 (DMXL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K151 Ubiquitination PhosphoSitePlus
T167 Phosphorylation PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
C276 Methylation IEDB 31844290
R315 Methylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus   UniProt 21406692
S425 Phosphorylation PhosphoSitePlus
S429 Phosphorylation PhosphoSitePlus
S436 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 21406692, 23186163, ...20068231
S487 Phosphorylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
T573 Phosphorylation PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus
Y702 Phosphorylation PhosphoSitePlus
S717 Phosphorylation PhosphoSitePlus
S719 Phosphorylation PhosphoSitePlus
K781 Ubiquitination PhosphoSitePlus
C812 Methylation IEDB 31844290
K849 Ubiquitination PhosphoSitePlus
K899 Ubiquitination PhosphoSitePlus
T902 Phosphorylation PhosphoSitePlus
K903 Ubiquitination PhosphoSitePlus
Y915 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S916 Phosphorylation PhosphoSitePlus
S917 Phosphorylation PhosphoSitePlus
S918 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 19664994, 18452278, ...18669648, 20068231
S924 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K929 Ubiquitination PhosphoSitePlus
K1062 Ubiquitination PhosphoSitePlus
K1178 Ubiquitination PhosphoSitePlus
K1190 Ubiquitination PhosphoSitePlus
K1196 Ubiquitination PhosphoSitePlus
S1258 Phosphorylation PhosphoSitePlus
S1261 Phosphorylation PhosphoSitePlus
S1271 Phosphorylation PhosphoSitePlus
S1285 Phosphorylation PhosphoSitePlus
T1287 Phosphorylation PhosphoSitePlus
S1288 Phosphorylation PhosphoSitePlus
K1343 Ubiquitination PhosphoSitePlus
S1347 Phosphorylation IEDB 35494241
S1373 Phosphorylation PhosphoSitePlus
T1375 Phosphorylation PhosphoSitePlus
S1377 Phosphorylation PhosphoSitePlus
S1379 Phosphorylation PhosphoSitePlus
S1381 Phosphorylation PhosphoSitePlus
S1426 Phosphorylation PhosphoSitePlus
S1427 Phosphorylation PhosphoSitePlus
S1430 Phosphorylation PhosphoSitePlus
K1434 Ubiquitination PhosphoSitePlus
T1521 Phosphorylation PhosphoSitePlus
S1601 O-Glycosylation GlyGen 30379171, 29351928
K1683 Ubiquitination PhosphoSitePlus
K1691 Ubiquitination PhosphoSitePlus
S1733 Phosphorylation PhosphoSitePlus
S1754 Phosphorylation PhosphoSitePlus
S1830 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1831 Phosphorylation PhosphoSitePlus
T1833 Phosphorylation PhosphoSitePlus
T1841 Phosphorylation PhosphoSitePlus
S1895 Phosphorylation PhosphoSitePlus
S1896 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T1900 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S1901 Phosphorylation PhosphoSitePlus
S1905 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1907 Phosphorylation PhosphoSitePlus
S1908 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 23186163
S1936 Phosphorylation PhosphoSitePlus
S1970 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 18452278, 19651622, ...24275569, 19690332, 20068231
K1987 Ubiquitination PhosphoSitePlus
Y2004 Phosphorylation PhosphoSitePlus
T2043 Phosphorylation PhosphoSitePlus
K2108 Ubiquitination PhosphoSitePlus
S2275 Phosphorylation PhosphoSitePlus
S2399 Phosphorylation PhosphoSitePlus
S2403 Phosphorylation PhosphoSitePlus
T2407 Phosphorylation PhosphoSitePlus
S2414 Phosphorylation PhosphoSitePlus
S2443 Phosphorylation PhosphoSitePlus
S2444 Phosphorylation PhosphoSitePlus
T2504 O-Glycosylation GlyGen 30379171, 29351928
K2582 Methylation PhosphoSitePlus
R2734 Methylation PhosphoSitePlus
C2884 Methylation IEDB 31844290
S2947 Phosphorylation PhosphoSitePlus
S3013 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S429 Y429 Biomuta DOID:1612 / breast cancer [ cosmic ]
S436 Y436 Biomuta DOID:363 / uterine cancer [ icgc ]
Y702 C702 Biomuta DOID:363 / uterine cancer [ icgc ]
S717 T717 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S916 C916 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S916 Y916 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S918 F918 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1343 E1343 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1373 C1373 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S1373 Y1373 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T1375 I1375 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T1375 A1375 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1377 G1377 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1381 C1381 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S1381 N1381 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1426 T1426 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1427 G1427 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1427 R1427 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1601 C1601 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K1683 N1683 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S1831 T1831 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T1900 I1900 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1905 F1905 Biomuta DOID:363 / uterine cancer [ cosmic ]
S1907 F1907 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T2043 A2043 Biomuta DOID:2394 / ovarian cancer [ icgc ]
S2399 Y2399 Biomuta DOID:363 / uterine cancer [ icgc ]
S2403 C2403 Biomuta DOID:1612 / breast cancer [ icgc ]
S2414 N2414 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]