iPTMnet Report for Q9Y483 (MTF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y483 / MTF2_HUMAN
Protein Name Metal-response element-binding transcription factor 2
Gene Name Name: MTF2
Synonyms:PCL2;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y483
DAG View
PRO Name metal-response element-binding transcription factor 2 (human)
Definition A metal-response element-binding transcription factor 2 that is encoded in the genome of human.
Short Label hMTF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y483 (MTF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
T24 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S27 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T29 Phosphorylation PhosphoSitePlus
K30 Methylation PhosphoSitePlus
K45 Methylation PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
C252 Methylation IEDB 31844290
K313 Ubiquitination PhosphoSitePlus
Y327 Phosphorylation PhosphoSitePlus
K378 Methylation PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
K412 Methylation PhosphoSitePlus
K416 Methylation PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
S438 Phosphorylation PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus   UniProt 23186163
K463 Ubiquitination PhosphoSitePlus
Y474 Phosphorylation PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
R480 Methylation PhosphoSitePlus
S488 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K522 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T24 Phosphorylation HPRD 18669648
S27 Phosphorylation HPRD 18669648
S488 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K30 E30 Biomuta DOID:3571 / liver cancer [ cosmic ]
K45 Q45 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K161 Q161 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K313 Q313 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K424 T424 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S452 L452 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S452 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S479 F479 Biomuta DOID:4159 / skin cancer [ cosmic ]
S488 Y488 Biomuta DOID:363 / uterine cancer [ icgc ]