iPTMnet Report for Q9Y458 (TBX22)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y458 / TBX22_HUMAN
Protein Name T-box transcription factor TBX22
Gene Name Name: TBX22
Synonyms:TBOX22;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y458
DAG View
PRO Name T-box transcription factor TBX22 (human)
Definition A T-box transcription factor TBX22 that is encoded in the genome of human.
Short Label hTBX22
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y458 (TBX22) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K63 Sumoylation PhosphoSitePlus
T68 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
Y138 Phosphorylation PhosphoSitePlus
T243 Phosphorylation PhosphoSitePlus
T268 Phosphorylation PhosphoSitePlus
K271 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K63 N63 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T68 A68 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S69 C69 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S69 F69 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S83 R83 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y138 C138 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T243 N243 Biomuta DOID:1324 / lung cancer [ cosmic ]
T268 M268 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
T268 R268 Biomuta DOID:3571 / liver cancer [ cosmic ]
T268 P268 Biomuta DOID:9256 / colorectal cancer [ cosmic ]