iPTMnet Report for Q9Y3Z3 (SAMHD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y3Z3 / SAMH1_HUMAN
Protein Name Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Gene Name Name: SAMHD1
Synonyms:MOP5;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y3Z3
DAG View
PRO Name deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (human)
Definition A deoxynucleoside triphosphate triphosphohydrolase SAMHD1 that is encoded in the genome of human.
Short Label hSAMHD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y3Z3 (SAMHD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
S6 Phosphorylation PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
T21 Phosphorylation IEDB   PhosphoSitePlus 31848261
S23 Phosphorylation PhosphoSitePlus
T25 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23186163, 27482511, 24275569
K66 Ubiquitination PhosphoSitePlus
T74 O-Glycosylation GlyGen 23301498, 29351928, 34019948, ...33391506, 28510447, 34229054
S84 O-Glycosylation GlyGen 23301498, 29351928, 34019948, ...33391506, 28510447, 34229054
S93 O-Glycosylation GlyGen 23301498, 29351928, 34019948, ...33391506, 28510447, 34229054
S93 Phosphorylation PhosphoSitePlus   UniProt 23186163
K98 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
Y103 Phosphorylation PhosphoSitePlus
T138 Phosphorylation PhosphoSitePlus
Y146 Phosphorylation PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
K294 Acetylation PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
Y315 Phosphorylation PhosphoSitePlus
K332 Sumoylation PhosphoSitePlus
C341 Methylation IEDB 31844290
K354 Acetylation PhosphoSitePlus
T384 Phosphorylation PhosphoSitePlus
T387 Phosphorylation PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
Y419 Phosphorylation PhosphoSitePlus
Y432 Phosphorylation PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
K455 Ubiquitination PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
K469 Sumoylation PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
S482 Phosphorylation PhosphoSitePlus
K486 Ubiquitination PhosphoSitePlus
Y507 Phosphorylation PhosphoSitePlus
S519 Phosphorylation PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
K544 Ubiquitination PhosphoSitePlus
Y553 Phosphorylation PhosphoSitePlus
K560 Ubiquitination PhosphoSitePlus
T579 Phosphorylation PhosphoSitePlus
T592 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 31291580, 27511536, 26121641, ...29515139, 27229711, 30044979, 28793904, 29321329, 34321470, 31375673, 23601106, 32209460, 18691976, 23186163, 25847232, 31950591, 18234856, 27815502, 26851491, 24275569, 29884836, 26294762, 26431200, 29610582, 25038827, 24623419, 18847512, 30039733, 26101257, 24035396, 26923586, 31797533, 25158827, 28321930, 29698322, 29587790, 19369195, 17081983, 24445253, 29084722, 36309692, 18669648, 35801923, 34513928, 30104243, 29670289, 20068231, 23602554
T592 Phosphorylation P06493 (CDK1) PhosphoSitePlus   RLIMS-P+   Signor 23601106, 24623419, 18234856, ...25847232, 23602554
T592 Phosphorylation P24941 (CDK2) PhosphoSitePlus   RLIMS-P+ 24623419, 18847512, 25847232
K595 Sumoylation PhosphoSitePlus
K596 Ubiquitination PhosphoSitePlus
S601 O-Glycosylation GlyGen 23301498, 29351928, 34019948, ...33391506, 28510447, 34229054
S601 Phosphorylation PhosphoSitePlus
T608 Phosphorylation PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus
K622 Sumoylation PhosphoSitePlus
K622 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S27 Phosphorylation HPRD 20166139
S33 Phosphorylation HPRD 20166139
S102 Phosphorylation HPRD 20068231
Y103 Phosphorylation HPRD 20068231
T138 Phosphorylation HPRD 20068231
T384 Phosphorylation HPRD 20068231
T387 Phosphorylation HPRD 20068231
T592 Phosphorylation HPRD 19413330, 18691976, 17081983, ...19664994, 19651622, 18669648, 20068231