iPTMnet Report for Q9Y3X0 (CCDC9)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y3X0 / CCDC9_HUMAN
Protein Name Coiled-coil domain-containing protein 9
Gene Name Name: CCDC9
Organism Homo sapiens (Human)

PRO ID PR:Q9Y3X0
DAG View
PRO Name coiled-coil domain-containing protein 9 (human)
Definition A coiled-coil domain-containing protein 9 that is encoded in the genome of human.
Short Label hCCDC9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y3X0 (CCDC9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S60 Phosphorylation PhosphoSitePlus
S80 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 23186163, 24275569, ...20068231
T83 Phosphorylation HPRD   PhosphoSitePlus 19413330
R94 Methylation PhosphoSitePlus
T95 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
R102 Methylation PhosphoSitePlus
R107 Methylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
R110 Methylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus   UniProt 23186163
S115 Phosphorylation PhosphoSitePlus
R121 Methylation PhosphoSitePlus
R128 Methylation PhosphoSitePlus
R130 Methylation PhosphoSitePlus
R131 Methylation PhosphoSitePlus   UniProt 24129315
R133 Methylation PhosphoSitePlus   UniProt 24129315
R135 Methylation PhosphoSitePlus   UniProt 24129315
S137 Phosphorylation PhosphoSitePlus   UniProt 23186163
K166 Ubiquitination PhosphoSitePlus
Y177 Phosphorylation PhosphoSitePlus
S202 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
R221 Methylation PhosphoSitePlus
R243 Methylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus   UniProt 23186163
S255 Phosphorylation PhosphoSitePlus   UniProt 23186163
S262 Phosphorylation PhosphoSitePlus
Y264 Phosphorylation PhosphoSitePlus
T286 Phosphorylation PhosphoSitePlus
Y316 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
K348 Acetylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
K355 Acetylation PhosphoSitePlus
Y361 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
S376 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163, 20068231
T381 Phosphorylation HPRD   PhosphoSitePlus 17081983
T385 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 18669648, 18220336
S386 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 17081983, ...15302935, 19664995, 18669648, 20068231
T389 Phosphorylation PhosphoSitePlus
S390 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 19651622, 23186163
T485 Phosphorylation PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
S521 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18767875, ...15302935, 18669648, 19690332, 20068231
S530 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S60 L60 Biomuta DOID:1725 / peritoneum cancer [ cosmic ]
R94 Q94 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T95 S95 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R102 L102 Biomuta DOID:3571 / liver cancer [ cosmic ]
R107 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S109 L109 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
R110 L110 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
R121 Q121 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R128 S128 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R128 H128 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
R130 Q130 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ]
R133 L133 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R135 Q135 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K166 N166 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S202 N202 Biomuta DOID:1319 / brain cancer [ cosmic ]
R221 C221 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R243 Q243 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S262 W262 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K348 R348 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K348 N348 Biomuta DOID:1319 / brain cancer [ icgc ]
S390 F390 Biomuta DOID:4159 / skin cancer [ cosmic ]
T485 M485 Biomuta DOID:3571 / liver cancer [ cosmic ]
S521 F521 Biomuta DOID:1324 / lung cancer [ cosmic ]