iPTMnet Report for Q9Y3R5 (DOP1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y3R5 / DOP2_HUMAN
Protein Name Protein dopey-2
Gene Name Name: DOP1B
Synonyms:C21orf5,DOPEY2,KIAA0933;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y3R5
DAG View
PRO Name protein dopey-2 (human)
Definition A protein dopey-2 that is encoded in the genome of human.
Short Label hDOP1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y3R5 (DOP1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
Y218 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
T284 Phosphorylation PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
K420 Ubiquitination PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
K538 Ubiquitination PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
K564 Acetylation PhosphoSitePlus
K570 Acetylation PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
K585 Ubiquitination PhosphoSitePlus
S589 Phosphorylation PhosphoSitePlus
S596 Phosphorylation PhosphoSitePlus
S597 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
S650 Phosphorylation PhosphoSitePlus
S681 Phosphorylation PhosphoSitePlus
K693 Methylation PhosphoSitePlus
S705 Phosphorylation PhosphoSitePlus
K710 Ubiquitination PhosphoSitePlus
S714 Phosphorylation PhosphoSitePlus
S716 Phosphorylation PhosphoSitePlus
S717 Phosphorylation PhosphoSitePlus
S718 Phosphorylation PhosphoSitePlus
S720 Phosphorylation PhosphoSitePlus
S721 Phosphorylation PhosphoSitePlus
K849 Ubiquitination PhosphoSitePlus
S936 Phosphorylation PhosphoSitePlus
S948 Phosphorylation PhosphoSitePlus
T951 Phosphorylation PhosphoSitePlus
S952 Phosphorylation PhosphoSitePlus
S956 Phosphorylation PhosphoSitePlus
K1007 Ubiquitination PhosphoSitePlus
S1021 Phosphorylation PhosphoSitePlus
S1035 Phosphorylation PhosphoSitePlus
S1085 Phosphorylation PhosphoSitePlus
S1159 Phosphorylation PhosphoSitePlus
S1167 Phosphorylation PhosphoSitePlus
S1169 Phosphorylation PhosphoSitePlus
K1175 Ubiquitination PhosphoSitePlus
S1177 Phosphorylation PhosphoSitePlus
S1183 Phosphorylation PhosphoSitePlus
S1193 Phosphorylation PhosphoSitePlus
S1194 Phosphorylation PhosphoSitePlus
S1263 Phosphorylation PhosphoSitePlus
Y1295 Phosphorylation PhosphoSitePlus
Y1330 Phosphorylation PhosphoSitePlus
S1361 Phosphorylation PhosphoSitePlus
K1570 Ubiquitination PhosphoSitePlus
K1645 Acetylation PhosphoSitePlus
K1645 Ubiquitination PhosphoSitePlus
K1655 Acetylation PhosphoSitePlus
S1658 Phosphorylation PhosphoSitePlus
S1659 Phosphorylation PhosphoSitePlus
T1664 Phosphorylation PhosphoSitePlus
T1665 Phosphorylation PhosphoSitePlus
Y1932 Phosphorylation PhosphoSitePlus
K1965 Ubiquitination PhosphoSitePlus
T2065 Phosphorylation PhosphoSitePlus
S2084 Phosphorylation IEDB 35494241
S2161 Phosphorylation PhosphoSitePlus
T2267 Phosphorylation PhosphoSitePlus
S2277 Phosphorylation IEDB 35494241
Site PTM Type PTM Enzyme Score Source PMID
S1658 Phosphorylation HPRD 17924679


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K65 R65 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y218 C218 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K570 R570 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S580 L580 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ icgc ]
S705 F705 Biomuta DOID:4159 / skin cancer [ cosmic ]
S716 L716 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S718 L718 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ]
S936 F936 Biomuta DOID:4159 / skin cancer [ cosmic ]
S948 I948 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S948 T948 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1021 L1021 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1159 L1159 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1175 T1175 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1361 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S1658 C1658 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1659 F1659 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
T1664 I1664 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2084 C2084 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]