iPTMnet Report for Q9Y3R0 (GRIP1)
Protein Information
| UniProt AC / UniProt ID | Q9Y3R0 / GRIP1_HUMAN |
| Protein Name | Glutamate receptor-interacting protein 1 |
| Gene Name | Name: GRIP1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y3R0 |
| PRO Name | glutamate receptor-interacting protein 1 (human) |
| Definition | A glutamate receptor-interacting protein 1 that is encoded in the genome of human. |
| Short Label | hGRIP1 |
| Category | organism-gene |
Q9Y3R0 (GRIP1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S28 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S43 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K49 | Acetylation | score1 | PhosphoSitePlus | |||
| S177 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S285 | O-Glycosylation | score1 | GlyGen | 23271734, 30620550 | ||
| S285 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S287 | O-Glycosylation | score1 | GlyGen | 23271734, 30620550 | ||
| S287 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S308 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R435 | Methylation | score1 | PhosphoSitePlus | |||
| T437 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S498 | Phosphorylation | score1 | IEDB | 31848261 | ||
| T532 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S609 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T614 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T616 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S661 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T711 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S725 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S726 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S727 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S734 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S762 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S773 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S845 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S847 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T850 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S854 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S863 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T928 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S953 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T972 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S996 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1048 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1097 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1103 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S918 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T919 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S921 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T928 | Phosphorylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
| PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
|---|---|---|---|---|---|---|---|
| Phosphorylation | P42262 (GRIA2) | S880 | Q9Y3R0 (GRIP1) | decreased_association | eFIP | 10501226 | |
| Phosphorylation | P42262 (GRIA2) | S880 | Q9Y3R0 (GRIP1) | decreased_association | eFIP | 11007883 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S285 | P285 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| T437 | A437 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T532 | I532 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S661 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
| S725 | G725 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S727 | N727 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S762 | I762 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S854 | C854 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S863 | N863 | Biomuta | [ cosmic ] | |
| S996 | C996 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S996 | Y996 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| S1097 | N1097 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View