iPTMnet Report for Q9Y3Q8 (TSC22D4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y3Q8 / T22D4_HUMAN
Protein Name TSC22 domain family protein 4
Gene Name Name: TSC22D4
Synonyms:THG1;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y3Q8
DAG View
PRO Name TSC22 domain family protein 4 (human)
Definition A TSC22 domain family protein 4 that is encoded in the genome of human.
Short Label hTSC22D4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y3Q8 (TSC22D4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
T57 Phosphorylation PhosphoSitePlus   UniProt 23186163
S62 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 18669648, 23186163
S69 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
T139 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
S165 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 23186163, 20068231
T167 Phosphorylation PhosphoSitePlus
S177 Phosphorylation IEDB   PhosphoSitePlus 35494241
K180 Acetylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus   UniProt 23186163
S207 Phosphorylation PhosphoSitePlus
T211 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18088087
S225 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T229 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569
S233 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S260 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
Y268 Phosphorylation phospho.ELM 18669648
T270 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S279 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 24275569, ...18088087, 19690332, 20068231
S306 Phosphorylation PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
S370 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S394 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S49 Phosphorylation HPRD 20058876
S62 Phosphorylation HPRD 19651622, 18669648, 18088087
S69 Phosphorylation HPRD 18452278
S70 Phosphorylation HPRD 18452278
S132 Phosphorylation HPRD 20068231
T139 Phosphorylation HPRD 20068231
T157 Phosphorylation HPRD 20068231
S158 Phosphorylation HPRD 20068231
S165 Phosphorylation HPRD 19651622, 18088087, 20068231
S187 Phosphorylation HPRD 18691976
T211 Phosphorylation HPRD 18669648, 18088087
S225 Phosphorylation HPRD 18669648
T229 Phosphorylation HPRD 17322306, 18669648, 20068231
S233 Phosphorylation HPRD 17322306, 18669648
Y268 Phosphorylation HPRD 18669648
T270 Phosphorylation HPRD 18669648
S279 Phosphorylation HPRD 19651622, 18088087, 18669648, ...19664994, 20068231
S370 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S24 G24 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S62 F62 Biomuta DOID:4159 / skin cancer [ cosmic ]
S69 F69 Biomuta DOID:4159 / skin cancer [ cosmic ]
S70 F70 Biomuta DOID:4159 / skin cancer [ cosmic ]
S123 Y123 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S177 I177 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S263 R263 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y268 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S306 N306 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S394 F394 Biomuta DOID:4159 / skin cancer [ cosmic ]