iPTMnet Report for Q9Y3L5 (RAP2C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y3L5 / RAP2C_HUMAN
Protein Name Ras-related protein Rap-2c precursor
Gene Name Name: RAP2C
Organism Homo sapiens (Human)

PRO ID PR:Q9Y3L5
DAG View
PRO Name Ras-related protein Rap-2c (human)
Definition A Ras-related protein Rap-2c that is encoded in the genome of human.
Short Label hRAP2C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y3L5 (RAP2C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y4 Phosphorylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
S17 Phosphorylation HPRD 20068231
T20 Phosphorylation HPRD 20068231
T25 Phosphorylation HPRD 20068231
T27 Phosphorylation HPRD 20068231
K31 Ubiquitination PhosphoSitePlus
Y40 Phosphorylation PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
T61 Phosphorylation PhosphoSitePlus
S66 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y106 Phosphorylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
K150 Acetylation IEDB 34357683
Y166 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K5 N5 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S11 R11 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K42 N42 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T61 S61 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K108 N108 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K148 I148 Biomuta DOID:9256 / colorectal cancer [ cosmic ]