Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9Y3I1 / FBX7_HUMAN
Protein Name F-box only protein 7
Gene Name Name: FBXO7
Organism Homo sapiens (Human)

DAG View
PRO Name F-box only protein 7 (human)
Definition An F-box only protein 7 that is encoded in the genome of human.
Short Label hFBXO7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9Y3I1 (FBXO7) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K227 Ubiquitination PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
C286 S-Nitrosylation dbSNO 19483679
K287 Ubiquitination PhosphoSitePlus
K289 Acetylation PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
T384 Phosphorylation PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
R451 Methylation PhosphoSitePlus
R479 Methylation PhosphoSitePlus
R481 Methylation PhosphoSitePlus
R498 Methylation PhosphoSitePlus
R504 Methylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S283 F283 Biomuta DOID:363 / uterine cancer [ tcga ]
S283 Y283 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
C286 R286 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
R451 I451 Biomuta DOID:363 / uterine cancer [ tcga ]
R481 C481 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R481 H481 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc ]
R498 * Biomuta DOID:9256 / colorectal cancer [ icgc ]