iPTMnet Report for Q9Y3E5 (PTRH2)
Protein Information
| UniProt AC / UniProt ID | Q9Y3E5 / PTH2_HUMAN |
| Protein Name | Peptidyl-tRNA hydrolase 2, mitochondrial |
| Gene Name | Name: PTRH2 Synonyms:BIT1,PTH2;ORFNames:CGI-147; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y3E5 |
| PRO Name | peptidyl-tRNA hydrolase 2, mitochondrial (human) |
| Definition | A peptidyl-tRNA hydrolase 2, mitochondrial that is encoded in the genome of human. |
| Short Label | hPTRH2 |
| Category | organism-gene |
DAG ViewQ9Y3E5 (PTRH2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Ubiquitination | score1 | PRO | ||||
| S5 | Phosphorylation | Q15139 (PRKD1) | score3 | neXtProt PhosphoSitePlus RLIMS-P Signor | 18703509 | |
| T45 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K47 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
| T48 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T50 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T52 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S54 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S57 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648, 19415658 | ||
| S62 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K76 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
| K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K81 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
| C86 | Methylation | score1 | IEDB | 31844290 | ||
| S87 | Phosphorylation | Q15139 (PRKD1) | score3 | neXtProt PhosphoSitePlus RLIMS-P Signor | 18703509 | |
| Y94 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K95 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
| K106 | Acetylation | score1 | PhosphoSitePlus | |||
| K106 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
| K115 | Ubiquitination | score1 | UniProt | 25621951 | ||
| K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K134 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T139 | Phosphorylation | score0 | HPRD | 20068231 | ||
| K171 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
| K177 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000048970 (hPTRH2/TransPep-/UbiqLys+) | ub | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T45 | M45 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K47 | N47 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S62 | I62 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
