Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y3E5 / PTH2_HUMAN
Protein Name Peptidyl-tRNA hydrolase 2, mitochondrial precursor
Gene Name Name: PTRH2
Synonyms:BIT1,PTH2;ORFNames:CGI-147;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y3E5
DAG View
PRO Name peptidyl-tRNA hydrolase 2, mitochondrial (human)
Definition A peptidyl-tRNA hydrolase 2, mitochondrial that is encoded in the genome of human.
Short Label hPTRH2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y3E5 (PTRH2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Ubiquitination PRO
S5 Phosphorylation Q15139 (PRKD1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 18703509
T45 Phosphorylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus   UniProt 25621951
T48 Phosphorylation PhosphoSitePlus
T50 Phosphorylation PhosphoSitePlus
T52 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
S57 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 19415658
S62 Phosphorylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus   UniProt 25621951
K79 Ubiquitination PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus   UniProt 25621951
S87 Phosphorylation Q15139 (PRKD1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 18703509
Y94 Phosphorylation PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus   UniProt 25621951
K106 Acetylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus   UniProt 25621951
K115 Ubiquitination UniProt 25621951
K119 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
T139 Phosphorylation HPRD 20068231
K171 Ubiquitination PhosphoSitePlus   UniProt 25621951
K177 Ubiquitination PhosphoSitePlus   UniProt 25621951


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048970 (hPTRH2/TransPep-/UbiqLys+) ub PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S5 C5 Biomuta DOID:1324 / lung cancer [ tcga ]
T45 M45 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K47 N47 Biomuta DOID:363 / uterine cancer [ tcga ]
S62 R62 Biomuta DOID:3571 / liver cancer [ icgc ]
S62 I62 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]