iPTMnet Report for Q9Y3E1 (HDGFL3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y3E1 / HDGR3_HUMAN
Protein Name Hepatoma-derived growth factor-related protein 3
Gene Name Name: HDGFL3
Synonyms:HDGF2;ORFNames:CGI-142;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y3E1
DAG View
PRO Name hepatoma-derived growth factor-related protein 3 (human)
Definition A hepatoma-derived growth factor-related protein 3 that is encoded in the genome of human.
Short Label hHDGFRP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y3E1 (HDGFL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K10 Ubiquitination PhosphoSitePlus
K20 Ubiquitination PhosphoSitePlus
Y22 Phosphorylation PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
S108 Phosphorylation HPRD   PhosphoSitePlus 17081983
T110 Phosphorylation HPRD   PhosphoSitePlus 17081983
T117 Phosphorylation PhosphoSitePlus
S121 Phosphorylation HPRD   PhosphoSitePlus 18452278
S122 Phosphorylation HPRD   PhosphoSitePlus 18452278
S149 O-Glycosylation GlyGen 23301498, 30379171
Y150 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus   UniProt 21406692
S180 Phosphorylation PhosphoSitePlus
T189 Phosphorylation PhosphoSitePlus
T192 Phosphorylation PhosphoSitePlus
T193 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
T199 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y22 C22 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K66 E66 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S121 I121 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S162 Y162 Biomuta DOID:9256 / colorectal cancer [ cosmic ]