Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9Y3D6 / FIS1_HUMAN
Protein Name Mitochondrial fission 1 protein
Gene Name Name: FIS1
Organism Homo sapiens (Human)

DAG View
PRO Name mitochondrial fission 1 protein (human)
Definition A mitochondrial fission 1 protein that is encoded in the genome of human.
Short Label hFIS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9Y3D6 (FIS1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO   UniProt 19413330, 25944712
S10 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 24275569, 29480948
K25 Ubiquitination PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
K46 Acetylation PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
Y76 Phosphorylation PhosphoSitePlus
Y82 Phosphorylation PhosphoSitePlus
Y87 Phosphorylation PhosphoSitePlus
Y93 Phosphorylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus


PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036281 (hFIS1/Ac:1) acM1 PRO

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S31 A31 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]