iPTMnet Report for Q9Y3C6 (PPIL1)
Protein Information
UniProt AC / UniProt ID | Q9Y3C6 / PPIL1_HUMAN |
Protein Name | Peptidyl-prolyl cis-trans isomerase-like 1 |
Gene Name | Name: PPIL1 Synonyms:CYPL1;ORFNames:CGI-124,UNQ2425/PRO4984; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y3C6 |
PRO Name | peptidyl-prolyl cis-trans isomerase-like 1 (human) |
Definition | A peptidyl-prolyl cis-trans isomerase-like 1 that is encoded in the genome of human. |
Short Label | hPPIL1 |
Category | organism-gene |
Q9Y3C6 (PPIL1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K37 | Ubiquitination | score1 | PhosphoSitePlus | |||
K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
R72 | Methylation | score1 | PhosphoSitePlus | |||
S76 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y78 | Phosphorylation | score1 | PhosphoSitePlus | |||
K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
C133 | Methylation | score1 | IEDB | 31844290 | ||
T147 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S149 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18077418, 23186163 | ||
K161 | Sumoylation | score1 | PhosphoSitePlus | |||
K161 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R72 | L72 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
R72 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S149 | F149 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |