Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9Y3C6 / PPIL1_HUMAN
Protein Name Peptidyl-prolyl cis-trans isomerase-like 1
Gene Name Name: PPIL1
Organism Homo sapiens (Human)

DAG View
PRO Name peptidyl-prolyl cis-trans isomerase-like 1 (human)
Definition A peptidyl-prolyl cis-trans isomerase-like 1 that is encoded in the genome of human.
Short Label hPPIL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9Y3C6 (PPIL1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K37 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
R72 Methylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
Y78 Phosphorylation PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
T147 Phosphorylation HPRD   PhosphoSitePlus 20068231
S149 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18077418, 23186163
K161 Sumoylation PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R72 * Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc, tcga ]
S149 F149 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]