iPTMnet Report for Q9Y3C5 (RNF11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y3C5 / RNF11_HUMAN
Protein Name RING finger protein 11
Gene Name Name: RNF11
ORFNames:CGI-123;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y3C5
DAG View
PRO Name RING finger protein 11 (human)
Definition A RING finger protein 11 that is encoded in the genome of human.
Short Label hRNF11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y3C5 (RNF11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 20676133, 20213681
C4 S-Nitrosylation dbSNO 24105792
S10 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus   UniProt 23186163
S25 Phosphorylation PhosphoSitePlus
T30 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
T135 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P   Signor   UniProt 16123141
T135 Phosphorylation P31749 (AKT1) PhosphoSitePlus   Signor 16123141


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:Q9HAU4 (hSMURF2) Interaction PR:Q9Y3C5 (hRNF11) PRO 14755250


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S14 F14 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ]
S14 T14 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S54 R54 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T135 M135 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]