Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y3C4 / TPRKB_HUMAN
Protein Name EKC/KEOPS complex subunit TPRKB
Gene Name Name: TPRKB
ORFNames:CGI-121,My019;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y3C4
DAG View
PRO Name EKC/KEOPS complex subunit TPRKB (human)
Definition An EKC/KEOPS complex subunit TPRKB that is encoded in the genome of human.
Short Label hTPRKB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y3C4 (TPRKB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K21 Ubiquitination PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
T77 Phosphorylation PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S152 Phosphorylation HPRD 20068231
T160 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T77 A77 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K150 T150 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S152 Y152 Biomuta DOID:3571 / liver cancer [ icgc ]